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Your Donation Doubled

All annual fund gifts DOUBLED this week only, up to $500,000.

All annual fund gifts DOUBLED this week only, up to $500,000.
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American Red Cross of South Carolina

The American Red Cross of South Carolina provides vital services to South Carolinians including disaster relief, health and safety classes, blood collection for hospitals and services to the armed forces.
Shelter Heroes banner.
We need disaster relief volunteers.
Learn how you can become a Shelter Hero in your community.

With just a few hours of training, you can join a dedicated team of Red Cross volunteers ready to bring food, shelter, and comfort to your community when a hurricane or other disaster strikes. Be the help someone needs - get started today!

Learn More about Shelter heroes
PARA ESPAÑOL, VISITE AQUÍ
American Red Cross Lifesaving Awards medal
Recognize heroes. Inspire others.
Tell us stories and nominate lifesavers.
Visit LifesavingAwards.org

Events

red cross gala graphic
34th Annual Red Cross Gala

March 21, 2026

6:00 PM - 11:00 PM

Hyatt Regency Greenville

Please join us for our 34th Annual Red Cross Gala!

Get Involved

Wrapped up Red Cross blanket on a cot
Become a Volunteer
Your time and talent can make a real difference in people's lives.
Learn More
Man sitting in a chair giving blood and speaking with a phlebotomist
Students in a Red Cross CPR class practicing on a mannequin
Take a Class
Expert training that fits your schedule.
Find a Class

South Carolina Locations

Red Cross volunteer holding a Red Cross blanket and standing in a shelter surrounded by shelter cots
Chapter Locations
Find the local chapter near you

View Locations

Chapter Locations

Central SC Chapter (Regional Headquarters)
Get Directions
2751 Bull Street
Columbia, SC 29201
1-803-540-1200 Details
Lowcountry SC Chapter
Get Directions
2424-A City Hall Lane
North Charleston, SC 29406
1-843-764-2323 Details
Eastern SC Chapter Headquarters
Get Directions
3531 Pampas Drive
Myrtle Beach, SC 29577
1-843-477-0020 Details
Upstate SC Chapter
Get Directions
940 Grove Road
Greenville, SC 29605
1-864-271-8222 Details

Blood Donation Centers

The need for blood is constant and your contribution is important for a healthy and reliable blood supply. You will feel good knowing you've helped change a life. Schedule an appointment at one of our locations.

View Locations

List of blood locations

Columbia Red Cross Blood and Platelet Donation Center - SC
Get Directions
2751 Bull St
Columbia, SC 29201
1-800-RED CROSS Details
Charleston Red Cross Blood and Platelet Donation Center - West Ashley
Get Directions
2000 Sam Rittenberg Blvd
Charleston, SC 29407
1-800-RED CROSS Details
Mt. Pleasant Red Cross Blood and Platelet Donation Center
Get Directions
920 Houston Northcutt Blvd
Mount Pleasant, SC 29464
1-800-RED CROSS Details
Myrtle Beach Red Cross Blood and Platelet Donation Center
Get Directions
3681 Renee Drive, Unit #4
Myrtle Beach, SC 29579
1-800-RED CROSS Details

News

Photo of Lisa Miller-Wills
American Red Cross of South Carolina mourns loss of Lisa Miller-Wills
American Red Cross of South Carolina
January 13, 2026
Recovering after Helene: Community partnerships help restore home in Edgefield County
Nick Gibson
January 09, 2026
Two women stand side by side
Laura Basta shares her Red Cross Why: How You Can Be a Superhero
Laura Basta
December 23, 2025
Santa donating platelets
From the North Pole to the donation chair: Santa helps save lives this holiday season
Nick Gibson
December 16, 2025
View All

Press Releases

Red Cross Teeters on Blood Shortage Following the Holidays; Donors Have Chance to Win Trip to Super Bowl LX during National Blood Donor Month
January 05, 2026
Blood Community Unites to Thank America’s Volunteer Blood Donors as National Blood Donor Month Approaches
December 18, 2025
American Red Cross Elevates Instructor Excellence with Enhanced First Aid/CPR/AED Program
December 02, 2025
Red Cross: Community responders provide lifeline amid 2025 emergencies
November 17, 2025
View All

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