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Southern California Region

The American Red Cross Southern California Region serves San Diego, Imperial, Orange, Riverside and San Bernardino Counties. 

As we close out the year in the Southern California Region, we invite you to revisit some of our most meaningful stories — stories that show how the American Red Cross mission comes to life in our community every day.

Take a moment to explore how we’ve brought comfort, relief and hope to neighbors during their most challenging times.

View stories and give to your local Red Cross
Click the Details Links to View Chapter Locations

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List of blood locations

San Diego Region HQ
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3950 Calle Fortunada
San Diego, CA 92123
(858) 309-1200 Details
Orange County
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600 Parkcenter Dr.
Santa Ana, CA 92705
(714) 481-5300 Details
Riverside County
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6235 River Crest Drive, Suite A
Riverside, CA 92507
(888) 831-0031 Details
Palm Desert/Coachella Valley
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72559 CA-Highway 111
Palm Desert, CA 92260
(888) 831-0031 Details
Imperial County
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703 Industry Way, Suite 3
El Centro, CA 92243
(760) 352-4541 Details
San Bernardino County
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10600 Trademark Parkway, Suite 406
Rancho Cucamonga, CA 91730
(909) 888-1481 Details
Victorville/High Desert
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17199 Yuma Street, Suite 2
Victorville, CA 92395
(442) 286-0079 Details
American Red Cross - Twentynine Palms
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Family Service Center, Building 693, Suite 107
Twentynine Palms, CA 92278
(760) 830-6685 Details
American Red Cross - Fort Irwin
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1204 Normandy Dr.
Fort Irwin, CA 92310
(760) 380-3697 Details

Blood Donation Centers

The need for blood is constant and your contribution is important for a healthy and reliable blood supply. You will feel good knowing you've helped change a life. Schedule an appointment at one of our locations.

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Blood Location Centers

Laguna Hills Red Cross Blood, Platelet and Plasma Donation Center
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22971 Mill Creek Dr
Laguna Hills, CA 92653
1-800-RED CROSS Details
Santa Ana Red Cross Blood, Platelet and Plasma Donation Center
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600 Park Center Drive
Santa Ana, CA 92705
1-800-RED CROSS Details
Fountain Valley Red Cross Blood, Platelet and Plasma Donation Center
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17800 Newhope St
Fountain Valley, CA 92708
1-800-RED CROSS Details
Fullerton Red Cross Blood, Platelet and Plasma Donation Centers
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1379 S Harbor Blvd
Fullerton, CA 92832
1-800-RED CROSS Details
Kearny Mesa Red Cross Blood, Platelet and Plasma Donation Center
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4229 Ponderosa Ave, Suite C
San Diego, CA 92123
1-800-RED CROSS Details
Riverside American Red Cross Blood and Platelet Donation Center

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6235 River Crest Dr., Ste. A
Riverside, CA 92507
1-800-RED CROSS Details
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