After the war, members of the Junior Red Cross kept working to make children’s lives better, both overseas and here at home. Through the National Children's Fund, the Junior Red Cross aided war victims and refugees throughout Europe and helped fight against the influenza pandemic which struck both Europe and America. Funds were raised to help victims of fires, floods and tornados and to support Native American schools in the American Southwest. During the Great Depression Junior Red Cross members distributed surplus wheat and cotton, collected clothing and food and canned fruits and vegetables.
Junior Red Cross membership grew to almost 20 million during World War II. Activities ranged from the production of clothing, toys, furniture and art works to entertainment and recreational programs at military camps and hospitals.
Following World War II, the Junior Red Cross continued some traditional programs, such as assistance to war veterans and their families, disaster relief, and public health. The Red Cross introduced an International Student Work-Study Program, started a High School Chest Program which sent school supplies to students who had lost them in natural disasters and set up Leadership Development Centers for junior and senior high school and college students.